Best Nootropics for Inflammation and Arthritis

Nootropic Supplements Used for Arthritis and Inflammation

Arthritis and inflammation are a common plague amongst humankind. It can affect work life and personal life, even down to the most mundane, daily activities.  Some arthritis is so bad it even effects the simplest tasks, such as brushing one’s teeth or carrying in the groceries.  Inflammation and arthritis can affect typing, eating, exercising, or even walking. Finding a solution can be difficult, however, there are many holistic answers, including nootropics.


Top Nootropics Used for Anti-Inflammation

These are some of the best nootropics for arthritis and inflammation.

Black Hoof Mushroom

Black Hoof

Black Hoof Mushroom is a popular holistic herb used throughout many traditional Asian medicines (Chen et al., 2019). The mushroom is commonly used as an anti-inflammatory.  It is said that the powerful anti-inflammation benefits of Black Hoof come from its well-studied flavonoid polyphenol pigments (2019).  The mushroom contains potent polysaccharide-proteins which have been proven to speed up the healing process for burns, cuts, infections, and abrasions (Osinska-Jaroszuk, 2020). Black Hoof’s analgesic properties make it a wonderful choice for treating topical wounds (Chang et al., 2011).  It has also been known to be able to produce immunostimulatory action (Uskokovic et al., 2020).

Ginkgo Biloba

Ginkgo has been around for more than 190 million years, and it has found itself some wonderful roots in traditional and ancient Chinese medicine (Chevallier, 2016). It is one of the most powerful anti-inflammatory nootropics and can even reduce inflammation where nerve tissue damage is present. It has been especially helpful for people who suffer from multiple sclerosis symptoms.  Its anti-inflammatory properties partially come from its ability to provide enhanced blood flow to the central nervous system.  It can even support and strengthen nerve tissue (2016). The anti-inflammation effects are primarily found in its fruit and seed (Orr, 2014).  Ginkgo has been referred to as a tonic for the body (2014).  It is also known for its ability to significantly decrease oxidative stress and reduce neuroinflammation (Kaur et al., 2018).

Huperzine A

Huperzine A

Huperzine  A comes from the club moss plant and is a powerful contributor to traditional Chinese medicine (Zangara, 2003). The extract has been used to treat fever and general inflammation for hundreds of years (Qian & Ke, 2014). In fact, there are many studies which show the plant’s genuine efficacy in reducing fever (Skolnick, 1997).  There are also studies which prove its ability to reduce chronic inflammation (Wang et al., 2009).  It has also been shown to offer neuroprotective properties (Wang et al., 2008).

Lion’s Mane Mushroom

Lion’s Mane Mushroom has a long term place throughout Asian traditional medicine, offering incredible anti-inflammation and neuroprotective properties (Beshara et al., 2019). A recent study showed the nootropic’s powerful effects on macrophages (Mori et al., 2015).  These are large cells which lie stagnant in tissues at the site of infection or inflammation flare up.  Other studies have outlined the mushroom’s ability to relieve oxidative stress and inflammations which contribute to the pathogenesis of neurodegenerative conditions (Kushairi et al., 2019).

Longvida Curcumin

Lonvida Curcumin (Turmeric) is a very popular plant in India and Southern Asia for its powerful medicinal properties (Chevallier, 2016). The herb is very popular for its ability to reduce inflammation and reduce symptoms in arthritis patients (Gupte et al., 2019). In fact, long-term use of Turmeric can lead to general pain relief in arthritis patients (Chevallier, 2016).  It can be used to treat allergies, asthma, and even eczema.  It has even been suggested to have the power to reduce the risk of stroke and heart attack (2016).

Milk Thistle

Milk Thistle

Milk Thistle is commonly used medicinally in traditional cultures for its potent seed constituent, silymarin (Chevallier, 2016). There are studies which show the flavonoid silymarin can reduce inflammation (Ashraf et al., 2019).  It has also been suggested to offer a reduction of hay fever and allergy symptoms (Bakhshaee et al., 2011).

Nigella Sativa

Nigella Sativa may be a member of the buttercup family, but it is well-known for its potent medicinal applications (Orr, 2014).  Nigella (also known as Kalanji or Black Cumin) is popular for its anti-inflammation properties (Chevallier, 2016).  In fact, in the Middle East and India it is one of the most popular anti-inflammatory herbs, even being used to treat infection (Orr, 2014).  The seeds are commonly used to treat headache, migraine, and even toothaches (Chevallier, 2016).  There are studies which outline the nootropic’s ability to treat headaches of all types (Shakeri et al., 2016). It can even improve intestinal barrier function (2016).

Rhodiola Crenulate

Rhodiola, the “Golden Root,” is known throughout many traditional cultures as a powerful, general tonic herb (Orr, 2014). It is used to treat muscle damage, improve the immune system, and for its general anti-inflammatory properties (Beshara et al., 2019).

Tongkat Ali

Tongkat Ali is a potent nootropic supplement most popular in Indochina and Indonesia, being hailed as a versatile tonic and general health herb (Rehman et al., 2016). It can be used as a topical analgesic and as an antibiotic.  It has extremely powerful fever-reducing properties (2016).  It is also popular for its potent anti-inflammatory properties, even being able to offer pain relief (Han et al., 2016).  This is largely due to its ability to inactivate NF-kB signaling pathways (2016).

Last Notes On Using Anti-Inflammation Nootropic Supplements

Finding the right holistic answer for inflammation can require some basic trial and error; however, it is reasonably simple to find a nootropic combination which would help. Some people suffering from severe arthritis or inflammation may choose to make use of multiple nootropic supplements, while others find one is enough to reduce their suffering and improve their pain.  The nootropics on this list work great together, not only for inflammation, but in providing other, life-enhancing benefits as well.

A Note From NooFiles

This article is intended to be used for information only.  We want to remind you that consulting your physician is recommended before adding any dietary supplement of any kind to your daily regimen.


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