Best Nootropics for Digestive Support

Nootropic Supplements Used for Digestive Support

Digestive issues can be significantly inconvenient. They can hold one back from some of life’s experiences, and they can affect all aspects of life.  Fortunately, finding a nootropic supplement that works for digestive support is not so hard with a little trial and error.  There are nootropics which offer great digestive support (and other benefits) that can be added to nearly any nootropic stack.  This is a list of the best nootropics for the digestive system, and a little information about how they work.

Upset Stomach

Top Nootropics for Digestive Support

Although there are few nootropics which work well for the digestive system, these few nootropics work extremely well and make a great addition to any nootropic stack.  They even offer other benefits too!


L-Theanine is derrived from Camellia sinensis, more commonly known as tea and one of the most popular beverages consumed around the world (Twilley & Lall, 2018).  It is extremely popular throughout Asia, becoming one of the staples of their traditional medicines as well (Chevallier, 2016). L-Theanine has been revealed in recent research to support the microorganisms Gut Flora found within the digestive tract (Saeed et al., 2019). These bacteria help aid the digestive tract and even help combat some digestive disorders (Wang et al., 2012).  L-Theanine has puprportedly been able to reduce risk of infections within digestive organs (Li et al., 2016), and can even reduce the growth and spread of harmful bacteria (Saeed et al., 2019). One study even revealed that L-Theanine may have the potential to prevent gastrointestinal disorders (Koo & Cho, 2004).  There are also recent studies outlining the polysaccharides from the Camellia sinensis flower as having the ability to regulate gut health (Chen et al., 2019). It is worth reading about the other benefits offered by L-Theanine.

Poria Mushroom

Poria Mushroom

Poria Mushroom has been a long part of traditional Chinese medicine for its general boost to vitality and digestive support (Cheng et al., 2015). And although it has been around for thousands of years, it has recently begun to take foothold in modern medicine as well (Li et al., 2019). Specifically, Poria is used to aid the digestive tract, including the symptoms of diarrhea (2019).  It is even used to relax stomach ache (2019).  In addition to its stomach-relaxing properties, it is considered an effective diuretic, promoting the healthy production of urine (Huang et al., 2020). It is worth reading about the other benefits offered by Poria Mushroom.

Honorable Mentions

Some additional nootropics that benefit the digestive tract include Black Hoof Mushroom, Lemon Balm, and Nigella Sativa. Nigella sativa (or Black Cumin seeds) are purportedly amazing for the digestive tract, whether used in a culinary fashion or as a dietary supplement (Chevallier, 2016). They can relieve stomach pain, ease nausea, reduce bloating, and even eliminate flatulence (2016). Lemon Balm is a frequent supplement in European cultures for its ability to aid in digestion (Aubert et al., 2019). And Black Hoof Mushroom can help with gastroenteric dysfunction, diarrhea, and overall digestive health issues (Zhu et al., 2008)

Last Words of Wisdom on Using Digestive Support Nootropics

While there are many nootropics that might help a little with digestive support, some are clearly more appropriate than others. L-Theanine and Poria Mushroom are the forerunning winners when it comes to the digestion tract, and both offer a plethora of additional benefits as well! These reasons make these two nootropics the best choices for any nootropic stack looking for a digestive boost.  Some people even choose to use both in the same nootropic stack!

A Note From NooFiles

This article is intended to be used for information only.  We want to remind you that consulting your physician is recommended before adding any dietary supplement of any kind to your daily regimen.


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Chen, D., Chen, G., Ding, Y., Wan, P., Peng, Y., Chen, C., Ye, H.,, Zeng, X., and Ran, L. (2019). Polysaccharides from the flowers of tea (Camellia sinensis L.) modulate gut health and ameliorate cyclophosphamide-induced immunosuppression. Journal of Functional Foods. Vol. 61. DOI:

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Huang, Y., Hsu, N., Lu, K., Lin, Y., Lin, S., Lu, Y., Liu, W., Chen, M., and Sheen, L. (2020). Poria cocos water extract ameliorates the behavioral deficits induced by unpredictable chronic mild stress in rats by down-regulating inflammation. J Ethnopharmacol. Vol. 258. DOI: 10.1016/j.jep.2020.112566

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Saeed, M., Xu, Y., Zhang, T., Ren, Q., and Sun, Chao, (2019). 16S ribosomal RNA sequencing reveals a modulation of intestinal microbiome and immune response by dietary L-theanine supplementation in broiler chickens. Poultry Science. Vol. 98(2). Pp. 842-854. DOI: Twilley, D., and Lall, N. (2018). Are Medicinal Plants Effective for Skin Cancer? Medicinal Plants for Holistic Health and Well-Being. Academic Press. ISBN: 978-0-12-812475-8. DOI:

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