Best Nootropics for Memory and Memory Recall

Nootropic Supplements Used for Memory

As humans age, so does their fluid intelligence (Kievit et al., 2018).  Memory becomes slower, sluggish, and more difficult to access.  It can be hard to both remember things and recall those memories.  Fortunately, there are natural, holistic ways to better store and retrieve memory. There are many nootropic supplements known to produce better cognitive function and improved memory (Chevallier, 2016). And adding one or more nootropics for memory and cognitive function is ideal for most nootropic stacks.

Top 12 Nootropic Supplements for Memory

These are the best nootropics for any stacks focused on cognitive support, memory, and memory recall.

Bacopa Monnieri

Bacopa Monnieri

Bacopa is one of the most effective nootropics for cognitive benefits, including memory (Chevallier, 2016).  It also helps assist with executive function, concentration, learning, and overall cognitive function.  It has been proven to reduce actual learning time (2016).  Bacopa has a place in Ayurvedic medicine, being directly associated with the brain and bolstering mental acuity (Stough et al., 2001). Traditional Indian holistic healing is well-known for its insanely potent memory-boosting ability (Walker & Brown, 1998).  It has also been proven to improve the memory retrieval process (Stough, 2011).

Citicoline

Citicoline is proven to offer improved brain metabolism by manipulating numerous neurotransmitters (Secades & Lorenzo, 2006).  It has been shown through much empirical research to improve multiple cognitive rating scales.  Citicoline is also able to produce many neuroprotective effects, benefiting neuroendocrine cells. These cells are critical in sending and receiving information with the nervous system (2006). Citicoline can even reduce the progression of some neurodegenerative conditions and cognitive impairments (Grieb, 2014). Many studies have revealed Citicoline’s CDP potential to improve density of dopamine receptors (Gimenez et al., 1991) and ultimately improve learning and memory performance (Secades & Lorenzo, 2006). One study even suggested that the regular use of Citicoline can be used to directly reduce memory loss suffered from aging (Nakazaki et al., 2020).

Ginkgo Biloba

Ginko Biloba

Ginkgo Biloba has thousands of years of history of improving memory, concentration, and brain focus (Chevallier, 2016).  A lot of the herb’s memory-boosting abilities are attributed to its benefits to cerebral blood flow and blood circulation.  It has been proven that improving cerebral circulation provides a natural improvement to memory and concentration (2016). There are studies which outline the herb’s ability to improve short-term and long-term memory (Balch, 2010). These same studies even reveal the herb’s ability to improve the peripheral circulation system, which also enhances natural brain function (2010).

Gotu Kola

Gotu Kola may be one of the more versatile nootropics on this list, however, it most certainly retains its value in terms of a cognitive and memory enhancer. It is very frequently used throughout Eastern cultures for its ability to strengthen memory and cognitive function (Chevallier, 2016). Gotu Kola’s use as a cognitive enhancer and memory booster dates back thousands of years (Gohil et al., 2010). It has even been suggested as a way to “maximize one’s learning potential and memory” (Orr, 2014). Some studies have proven Gotu Kola’s ability to slow natural memory loss often suffered in elderly years (Walker & Brown, 1998). Gotu Kola is commonly used in Asian and Indian cultures for its ability to improve concentration, mostly thanks to its adaptogenic properties, concentration boost, and increase to attention span, alertness, and focus (Farhana et al., 2016).

Huperzine A

Huperzine A comes from a moss regularly hailed by chinese medicine for its abiltiy to improve cognitive function (Zangara, 2003). In fact, it has been used for thousands of years throughout traditional Chinese medicine for its memory-boosting capabilities (Walker & Brown, 1998). Even to this day it is used in Chinese culture for its memory-boosting and mental-capacity increasing properties (1998). Mostly these properties come from the herb’s ability to cross the blood-brain barrier (Zangara, 2003). This is the same reason the herb is able to produce many neuroprotective properties (2003). Huperzine A has proven its value to many patient’s suffering neurodegenerative disorders, espeically Alzheimer’s disease (Beshara et al., 2019). There are many recent studies which outline Huperzine A as an effective herb for combating the symptoms of Alzheimer’s and efficiently promoting boosts to overall memory (2019).

Lion’s Mane Mushroom

Lions-Mane

Lion’s Mane Mushroom is one of the most commonly mentioned nootropics when it comes to cognitive enhancement and memory. Recent studies have backed its notoriety as a memory booster, proving the herb can enhance cognitive function and improve overall mild cognitive impairment (Beshara et al., 2019). Lion’s Mane has most certainly asserted its strong influence on a variety of mental attributes including concentration, attention-span, and memory (Nagano et al., 2010). The mushroom has significantly proven its ability to boost overall cognitive function scores, including memory (Mori et al., 2009). This increase in cognitive ability and memory appears to increase with regular, daily use (2009). A lot of studies seem to indicate that the herb’s neuroprotective and antioxidant properties contribute heavily to its memory enhancing abilities (Kushari et al., 2019).

Longvida Curcumin

Tumeric (Longvide curcumin) is native to Asia and India and is commonly used as a nootropic for many purposes (Chevallier, 2016).  There have been a number of studies which have revealed Curcumin to have a significant ability to increase memory in many study participants (Cox et al., 2015).  These same studies also outline the herb’s ability to improve overall cognitive function.  Specifically, the study proved a higher attention span, and working memory performance (2015). There are many other studies which prove the herb offers powerful boosts to working memory, with these benefits stemming from its anti-amyloid brain effects (Small et al., 2018).  These study results show decreased plaque accumulation in the brain regions which are known to modulate memory (2018).

L-Theanine

L-Theanine is derrived from Camellia sinensis (aka herbal tea), and it is a part of the second highest beverage consumed on the planet (Twilley & Lall, 2018). While L-Theanine is well-known for its general boosts to cognitive performance, there are many modern studies which show the nootropic has the potential to improve concentration and learning ability (Vuong et al., 2011). Part of the nootropic’s improvement to memory and cognitive ability come from its ability to increase cerebral blood flow, especially when it is combined with caffeine (Dodd et al., 2015). These contributions to brain health are the reported reasons for the nootropic’s cognitive benefits (2015). L-Theanine supplies the brain with increased subjective alertness, which also benefits cognitive function (Giesbrecht et al., 2010).  This is one of the biggest reasons it improves performance of cognitive demanding tasks, especially surrounding memory (2010).

L-Tyrosine

Chemical Makeup

L-Tyrosine is a non-essential amino acid naturally manufactured by the body from the amino acid phenylalanine (Bloemendaal et al., 2018).  It is most commonly used to create proteins (Slominski et al., 2012). One of its monstrous, proven effects on the brain is its ability to improve cognitive performance in stressful situations (Young, 2007). Additionally, there are studies which back its ability to improve working memory and overall mental processing skills (Colzato et al., 2013).  For these reasons, the nootropic is typically used to replenish cognitive resources as needed. With so many modern studies proving the herb is able to bolster cognitive function (McTavish et al., 2005), it is a very wise addition to almost any nootropic stacks.

Panax Ginseng

Panax Ginseng is one of most well-known and used nootropic around the world for improving cognitive performance (Beshara, 2019).  There are a lot of clinical trials which prove the herb to offer significant benefits to cognitive function and working memory. For these reasons it is even used by Alzheimer’s patients and those suffering from dementia (2019). Ginseng has also been shown in a number of modern studies to improve overall mental activity, attention-span, alertness, and energy (Balch, 2010).

Poria Mushroom

Poria Mushroom has been used for more than two thousand years in traditional Chinese medicine (Li et al., 2019). It has been hailed a significant memory booster by many Eastern cultures (Lin et al., 2012).  Most of its cognitive benefits purportedly come from its ability to increase cerebral blood flow (Sun et al., 2021).  Its powerful memory-boosting properties make it an excellent treatment for dementia and memory repair (Lin et al., 2012). For these reasons, Poria Mushroom is commonly used to help treat a variety of neurogenetic disorders (2012).  It is also heavily associated with enhanced learning ability and associated memory recall (Wu et al., 2020).

Rhodiola Crenulate

Rhodiola Crenulata is also knonw as the “Golden Root” in many Eastern cultures (Orr, 2014). The herb itself survives in some of the most extreme environments and can be harder to come by. It offers one of the most powerful nootropic aids to cognitive ability, releasing mental tension and honing mental acuity (2014). It can also improve circulation to the brain and is well-known to act as a precursor for neurotransmitters used in cognitive function (Tabassum et al., 2012).  For these reasons, it is one of the most common nootropics selected for career-focused and entrepreneur nootropic stacks (2012). Sometimes, it is combined with Ginkgo Biloba to improve mental endurance (Zhang et al., 2009, Al-Kuraishy, 2015).

Final Words on Nootropic Supplements for Memory

All-in-all, there are many nootropics which offer natural boosts to memory and cognitive support.  The nootropics on this list are some of the most commonly used for memory storage and memory recall. They have some of the greatest historic, traditional use, and are easy to add to almost any nootropic stack. Some people use more than one memory nootropic, adding multiple selections to their nootropic stack to achieve an even greater memory effect.

A Note From NooFiles

This article is intended to be used for information only.  We want to remind you that consulting your physician is recommended before adding any dietary supplement of any kind to your daily regimen.

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Mori, K., Inatomi, S., Ouchi, K., Azumi, Y. and Tuchida, T. (2009). Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother. Res. Vol. 23. Pp. 367-372. DOI: https://doi.org/10.1002/ptr.2634

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The Nootropics Library: Curcumin (Turmeric)

Everything You Need to Know About Curcumin (Turmeric)

General Information

Scientific Name: Curcuma longa (of the Zingiberaceae family)

Any Other Names: Longvida Curcumin, Longvida Optimized Curcumin, Turmeric Curcumin, Haldi (Hindi), Jiang Huang (Chinese)

Primary Constituents: Curcumin, Curcuminoids (Demethoxycurcumin and Bidesmethoxycurcumin), Resin, Bitter Principles, Volatile Oils (Zingiberen and Turmerone)

Country or Region of Origin: Native to India and Southeast Asia, Cultivated in Regions Around 75 Degrees Fahrenheit with Heavy Rainfall

Known Uses: Cognitive Function, Memory, Mood, Anti-Fatigue, Anti-inflammation, Dye, Culinary Ingredient, and More

General History & Introduction

Turmeric is a bright yellow plant native to India and Southern Asia.  It is also found in many tropical regions, though it does require a humid climate and well-drained soil (Chevallier, 2016).  It has a long history of being used in Ancient Ayurvedic and Chinese medicines. It has been used to treat some short-term ailments, as well as more chronic health problems.  A lot of the research and empirical data currently being collected on the herb and its primary constituent, Curcumin, have been confirming the traditional uses of the plant (2016).

Turmeric has been a part of intercontinental trade since the early 1400s, becoming very popular in Europe as a result (Chevallier, 2016).  The Europeans believed that herbs like Curcumin allowed for greater longevity and healthier lives (2016).  This fad would catch on in North America in modern years with Turmeric becoming popular for cooking and its use as a dietary supplement.

Curcumin is an excellent, natural way to get a genuine boost to cognitive performance and memory (Kuszewski et al., 2018). It is a wonderful mood stabilizer, improving calmness and thwarting depression (Ramaholimihaso et al., 2020). The herb has been used to reduce fatigue and inflammation and has proven its worth in a variety of other ways (Chevallier, 2016).  It is reasonable to suggest Turmeric and Curcumin deserve more attention and research, so that the nootropics world can more fully understand the potential benefits.

Nootropic Benefits of Curcumin (Turmeric)

Cognitive Function and Memory

One study analyzed the long-term effects of Curcumin in healthy adults to find to significantly increased memory in study participants (Cox et al., 2015). This same study also outlined a recorded benefit in cognitive function. Specifically, the empirical data highlighted an improved state of attention and working memory tasks. This randomized, double-blind, placebo-controlled clinical trial also supported the claim that Curcumin can improve memory (2015). Recent studies have shown the herb’s positive effects on dementia and traumatic brain injury (Mishra & Palanivelu, 2008).  This same research outlined its additional benefit as an antioxidant, and as having the ability to improve cognitive function in Alzheimer’s patients (2008).

MEDICAL-JOURNAL

Many modern studies have begun to reveal curcumin’s true positive effects on cognitive function and working memory (Kuszewski et al., 2018). A recent, long-term double-blind, placebo-controlled trial of curcumin published in a popular psychiatry journal has uncovered more significant cognitive benefits stemming from its anti-amyloid brain effects (Small et al., 2018).  The study measured significant benefits which included improved memory and attention-span, and decreased plaque accumulation in the brain regions which modulate memory (2018).

Mood

A recent study showcased the nootropic’s ability to significantly improve mood (Cox et al., 2015). These studies report participants as experiencing a ‘state of calmness’ (2015). Another noteworthy study called Curcumin a generally “health-promoting” agent (Stohs et al., 2020).  Turmeric has been proven to offer mood enhancing effects which specifically treat depression (Ramaholimihaso et al., 2020). Not only can the herb help reduce symptoms of depression, but it has been proposed as a potential alternative treatment for managing Major Depressive Disorder (MDD) as well as reducing oxidative stress (2020). Some more recent research has outlined the results of a FDDNP-PET scan post Curcumin-treatment to reveal a decrease in plaque and tangle accumulation in the brain region which modulates mood (Small et al., 2018).

Anti-Fatigue

TIRED

Turmeric has been a traditional remedy for chronic fatigue throughout many Eastern cultures. In modern times, there have been studies which do prove Curcumin’s ability to reduce fatigue and fatigue-induced stress (Cox et al., 2015). One study showcased the supplement’s potential wide spectrum bioactivities which could be responsible for improving exercise performance, reducing fatigue, and promoting overall health (Huang et al., 2015). Curcumin has also been suggested to have the ability to reduce symptoms of chronic fatigue syndrome (Campen & Visser, 2019).

Anti-inflammation

One study outlines the nootropic’s ability to reduce inflammation, even pointing out the herb could ultimately alleviate symptoms in patients suffering from certain forms of arthritis (Gupte et al., 2019).  And although Turmeric is not directly used for pain relief, the anti-inflammation properties can make it a useful long-term treatment for arthritis, as it leads to reduced pain (Chevallier, 2016). It is also commonly used to treat allergies, asthma, and eczema for the same reason. These anti-inflammatory properties and the herb’s other effects make it an excellent choice for treating circulatory disorders. It has even been suggested to have the ability to reduce the risk of stroke and heart attack (2016).

Other Uses

Turmeric was well-known in Ayurvedic medicine as well, traditionally being used as a treatment for jaundice (Chevallier, 2016).  It would also become a part of many other herbal remedies as a bitter and for its various medicinal properties. Some of these benefits include antimicrobial properties, anti-platelet properties (thins the blood), and its ability to lower cholesterol levels. It can be used to treat athlete’s foot, and even motion sickness (2016).

While there is not currently enough information or research, Turmeric is being investigated for its potential to prevent certain types of cancers (Chevallier, 2016). It has been used to treat some skin conditions, including fungal infections and psoriasis. It is also used to treat and reduce nausea. And although unproven, it has been suggested to have the ability to prevent some autoimmune diseases (2016).

Dosing and Usage Information

Turmeric extract supplements usually offer 500 to 2000 mg daily servings, depending upon the extract ratio.  Generally only the rhizome, or roots, of the plant are used for culinary or medicinal purposes (Chevallier, 2016).  The roots are normally unearthed and broken into pieces, then boiled and dried before being further produced and manufactured.  Some preparations might include decoctions, powders, poultice (pastes), and herbal teas (2016).

Side Effects

Turmeric is generally accepted as safe when consumed as a dietary supplement within established daily values. Non-extracted products which offer up to 8 grams of curcumin in a daily serving are common. The rare side effects which can occur include diarrhea, dizziness, headache, and nausea (Hewlings & Kalman, 2017).

Conclusion

Although it is clear through the collection of many studies and clinical trials that Curcumin offers health benefits of various kinds (Stohs et al., 2020), more research will determine the full extent of these benefits. Still, enough research does exist to determine some baseline supplement benefits.  Curcumin is great for cognitive function, memory, and mood; and it is especially more useful with age (Cox et al., 2015).  In other words, while the supplement can help a young person in many ways, it will help older people with even greater effects. It can even purportedly prevent some aspects of mental decline altogether! And depending upon the goal of a nootropic stack, it is reasonable to find curcumin in many daily regimens.

A Note from NooFiles

This article is intended to be used for information only.  We want to remind you that consulting your physician is recommended before adding any dietary supplement of any kind to your daily regimen.

Sources:

Campen, L., & Visser, F. (2019). The Effect of Curcumin in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis Disparate Responses in Different Disease Severities. Pharmacovigilance and Pharmacoepidemiology. Edelweiss Publications. Vol. 2(1). Pp. 22-27. ISSN: 2638-8235

Chevallier, A. (2016). Encyclopedia of Herbal Medicine. Third Edition. DK Publishing. New York, New York. ISBN 978-1-4654-4981-8

Cox, K., Pipingas, A., and Scholey, A. (2015). Investigation of the effects of solid lipid curcumin on cognition and mood in a healthy older population. J Psychopharmacol. Vol. 29(5). Pp. 642-51. DOI: 10.1177/0269881114552744

Gupte, P., Giramkar, S., Harke, S., Kulkarni, S., Deshmukh, A., Hingorani, L., Mahajan, M., and Bhalerao, S. (2019). Evaluation of the efficacy and safety of Capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study. Journal of inflammation research. Vol. 12. Pp. 145–152. DOI: https://doi.org/10.2147/JIR.S205390

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Huang, W., Chiu, W., Chuang, H., Tang, D., Lee, Z., Wei, L., Chen, F., and Huang, C. (2015). Effect of curcumin supplementation on physiological fatigue and physical performance in mice. Nutrients. Vol. 7(2). Pp. 905–921. DOI: https://doi.org/10.3390/nu7020905

Kuszewski, J., Wong, R., and Howe, P. (2018). Can Curcumin Counteract Cognitive Decline? Clinical Trial Evidence and Rationale for Combining ω-3 Fatty Acids with Curcumin. Advances in Nutrition. Vol. 9(2). Pp. 105–113, DOI: https://doi.org/10.1093/advances/nmx013

Mishra, S., & Palanivelu, K. (2008). The effect of curcumin (turmeric) on Alzheimer’s disease: An overview. Annals of Indian Academy of Neurology. Vol. 11(1). Pp. 13–19. DOI: https://doi.org/10.4103/0972-2327.40220

Ramaholimihaso, T., Bouazzaoui, F., and Kaladjian, A. (2020). Curcumin in Depression: Potential Mechanisms of Action and Current Evidence-A Narrative Review. Frontiers in psychiatry. Vol. 11. PMID: 33329109 DOI: https://doi.org/10.3389/fpsyt.2020.572533

Small, G., Siddarth, P., Li, Z., Miller, K., Ercoli, L., Emerson, N., Martinez, J., Wong, K., Liu, J., Merrill, D., Chen, S., Henning, S., Satyamurthy, N., Huang, S., Heber, D., and Barrio, J. (2018).Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial. The American Journal of Geriatric Psychiatry. Vol. 26(3). Pp. 266-277. DOI: https://doi.org/10.1016/j.jagp.2017.10.010

Stohs, S., Chen, O., Ray, S., Ji, J., Bucci, L., and Preuss, H. (2020). Highly Bioavailable Forms of Curcumin and Promising Avenues for Curcumin-Based Research and Application: A Review. Molecules (Basel, Switzerland). Vol. 25(6). Pp. 1397. DOI: https://doi.org/10.3390/molecules25061397

The Nootropics Library: Gotu Kola

Everything You Need to Know About Gotu Kola

General Information

Scientific Name: Centella asiatica

Any Other Names: Indian Pennywort, Jalbrahmi, Hydrocotyle, Spadewort, Moneywort,

Primary Constituents: Alkaloids (hydrocotyline), Bitter principles (vellarin), and Triterpenoid saponins (such as asiaticoside, brahmoside, and thankuniside)

Country or Region of Origin: Gotu Kola originates in India and within the Southern United States, however, it can grow abundantly in any tropical or subtropical region of the world (including Australia, Africa, and South America); Typical growing grounds are marshy or near riverbanks (Chevallier, 2016);

Known Uses: Cognitive and Brain Function, Wound Healing and Eczema, General Vitality, Libido and Potency, and More

General History & Introduction

Gotu Kola is one of the most versatile herbs within the nootropics world.  It is a perennial and an herbaceous creeping plant which can grow as long as 20 inches (Chevallier, 2016).  The leaves are fan-shaped and have both medicinal and culinary uses.  It is a member of the Apiaceae family and popularly used and known as Indian Pennywort throughout Eastern cultures.  It can be used to strengthen memory and nervous function, to improve cognitive function and general vitality, and to improve libido (2016). In fact, it is a well-known nervine in traditional Eastern medicines (Orr, 2014).  Although the preparations may vary depending upon the intended use, the herb has a plethora of empirical data supporting its awesome nootropic benefits.

Nootropic Benefits of Gotu Kola

Brain Function and Memory

Gotu Kola has a long history of being used as a cognitive enhancer (Gohil et al., 2010). There have been many studies which have revealed the herb to possess the ability to improve memory (Farhana et al., 2016). This was especially proven true for elderly and stroke patients. This is probably because it possess the ability to slow memory loss (Walker & Brown, 1998). Indian and Asian cultures have used the plant for its ability to improve concentration.  Gotu Kola’s adaptogenic properties contribute to the focus and concentration boost.  A recent clinical trial revealed the plant’s ability to improve attention span and alertness (2016).  Gotu Kola promotes a relaxing concentration that decreases anxiety and gives the brain a chance to maximize its cognitive potential (Orr, 2014).

Wound Healing and Eczema

BANDAGE

Gotu Kola is well known to have positive effects on arthritis and rheumatic problems (Chevallier, 2016). It has even been suggested to have the ability to prevent rheumatic problems.  Its ability to improve peripheral circulation is useful in strengthening blood vessels.  It can be used to treat skin problems, help heal wounds and ulcers, and prevent scarring.  Usually, in traditional Ayurvedic medicine, the herb is applied directly as a salve to the wound or area of ailment for relief (2016). The plant can be used to heal and treat psoriasis, leprosy, lupus, and more (Gohil et al., 2010). It has also been proven to possess incredible healing effects on the bladder and the integrity of the connective tissues within the bladder (Murray & Pizzorno, 1998).  Gotu Kola can also be used to treat severe periodontal disease and the recovery after laser surgery (1998).

General Vitality

Gotu Kola has a profound reputation throughout India and many parts of Asia for its powerful rejuvenating effects (Chevallier, 2016). It is believed to have the ability to slow down aging (2016).  This may have a lot to do with the herb’s effects on memory and brain function, although, the libido boost could also be interpreted as energizing.  As an adaptogen, Indian culture typically suggests using the herb long-term to promote a variety of health benefits. Gotu Kola has been proven to speed up collagen formation and offers venous repair properties (2016).  It can be used to treat cellulite and varicose veins (Murray & Pizzorno, 1998). The plant can alleviate headaches and migraines (Gohil et al., 2010).  It was even a prime constituent in a popular Thailand energy drink known as “Pennywort” (Orr, 2014).

Libido and Potency

LIBIDO

Gotu Kola can provide a benefit to overall mood, releasing tension and encouraging libido (Chevallier, 2016).  The plant’s ability to improve circulation and poor blood flow may help contribute to its potency-improving effects, as well as the traditional belief the herb can help with erectile dysfunction (Qinna et al., 2009). In fact, one doctor, Virender Sodhi (MD) has well-documented Gotu Kola’s ability to improve erectile dysfunction, as well as its use as a general aphrodisiac (Sodhi, 2006).  It has even been suggested to improve testosterone (2006).  The herb can decrease fatigue, which also helps increase sex drive (Balch, 2010).

Other Uses

Gotu Kola is a tonic for many ailments. The aerial parts of the plant are known to have valuable cleansing properties and are typically made into powerful tonics (Chevallier, 2016).  In Indian culture, the fresh leaves are consumed raw in salads. The leaves possess an awesome tonic-like effect on digestion. Gotu Kola can also be used as an anti-inflammatory. The plant can be used as a peripheral vasodilator. It even possesses sedative properties and as previously mentioned, it can greatly reduce anxiety.  This makes sense, given the herb is a well-documented adaptogen (2016).

Dosing and Usage Information

Gotu Kola is typically used as a dietary supplement, with most serving sizes ranging between 500 and 1000 mg of extract per pill (Farhana et al., 2016).  As a powder, the herb has been used in traditional Ayurvedic medicine as a general tonic remedy (Chevallier, 2016).  Usually about 1-2 grams a day of the powder would be consumed in this fashion.  Sometimes Indian medicine will call for a paste to be made from the powder, which is the preferred method for treating eczema throughout the culture.  There are infusions which can be produced to treat rheumatism.  And there are tinctures for memory, concentration, and cognitive function (2016).

Side Effects

Gotu Kola does not have any known toxicity within the confines of a recommended dose (Gohil et al., 2010).  The side effects which do exist in rare cases include skin allergy, headache and dizziness, nausea, and drowsiness (2010).

Other Important Information

SEEDLING

Gotu Kola is typically cultivated from seed in the Springtime; however, the aerial parts can be harvested any time throughout the year (Chevallier, 2016). Triterpenoids saponins are the active constituents believed to be responsible for the medicinal and therapeutic properties of the planet (Gohil et al., 2010).  The plant also contains several nutrients including calcium, iron, magnesium, manganese, phosphorus, potassium, selenium, zinc, vitamins B 1-3, and vitamin c (Balch, 2010).

Conclusion

Gotu Kola is a powerful nootropic and adaptogen, offering many benefits to the body and the brain.  The herb helps maximize one’s learning potential and memory (Orr, 2014).  It has been used throughout traditional Ayurvedic medicine for thousands of years and has even been nicknamed the “miracle elixir of life” (Gohil et al., 2010). And it has literally been associated with the brain in traditional Ayurvedic culture and is even purported to have the ability to increase intelligence (Orr, 2014). All of the positive benefits of Gotu Kola, with so little side effects, arguably make it one of the strongest nootropics to date.

A Note from NooFiles

This article is intended to be used for information only.  We want to remind you that consulting your physician is recommended before adding any dietary supplement of any kind to your daily regimen.

Sources:

Balch, P. (2010). Prescription for Nutritional Healing. Fifth Edition. Avery Publishing. New York, New York. ISBN 978-1-58333-400-3

Chevallier, A. (2016). Encyclopedia of Herbal Medicine. Third Edition. DK Publishing. New York, New York. ISBN 978-1-4654-4981-8

Farhana, K., Malueka, R., Wibowo, S., & Gofir, A. (2016). Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke. Evidence-based complementary and alternative medicine. PMID: 2795915. DOI: https://doi.org/10.1155/2016/2795915

Gohil, K., Patel, J., & Gajjar, A. (2010). Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all. Indian journal of pharmaceutical sciences. Vol. 72(5). Pp. 546–556. DOI: https://doi.org/10.4103/0250-474X.78519

Murray, M., and Pizzorno, J., (1998). The Encyclopedia of Natural Medicine. Third Edition. Atria Paperback. ISBN 978-1-4516-6300-6

Orr, S. (2014). The New American Herbal. Clarkson Potter Publishers. New York, New York. ISBN 978-0-449-81993-7

Qinna, N., Taha, H., Matalka, K., and Badwan, A. (2009). A new herbal combination, Etana, for enhancing erectile function: an efficacy and safety study in animals. Int J Impot Res. Vol. 21(5). Pp.315-20. DOI: 10.1038/ijir.2009.18

Sodhi, V. (2006). Male Sexual Health: An Ayurvedic Perspective. Naturopathic Doctor News & Review. Retrieved from: https://ndnr.com/mens-health/male-sexual-health-an-ayurvedic-perspective/

Walker, L., and Brown, E. (1998). The Alternative Pharmacy. Prentice Hall Press. Paramus, New Jersey.  ISBN 0-7352-0021-1

The Nootropics Library: Ginkgo Biloba

Everything You Need to Know About Ginkgo Biloba

General Information

Scientific Name: Ginkgo Biloba (from the Ginkgoaceae family)

Any Other Names: Maidenhair Tree, Bai Guo (Chinese)

Primary Constituents: Bilobalides, Ginkgolides, Flavonoids

Country or Region of Origin: Native to China, Also Cultivated in France, South Carolina (United States)

Known Uses: Memory, Concentration, Circulatory and Blood Flow Issues, Antioxidant, Anti-inflammatory, Anti-allergenic, Asthma, Dementia, Depression, and More

General History & Introduction

Ginkgo is one of the oldest trees on the planet, if not the oldest, with the first growing dating beyond 190 million years old (Chevallier, 2016).  It has found its place in ancient, traditional Chinese medicine. Ginkgo’s medical and therapeutic uses have been well-researched in modern times as well.  In fact, it is one of the most widely used medicinal herbs in the Western world (Roland & Nergård, 2012). The leaves are typically turned into an extract which can be used to treat a variety of ailments and conditions. Some of these maladies include but are not limited to circulation and blood flow issues, asthma, allergies, weak bladder, incontinence, anti-inflammatory, antispasmodic, multiple sclerosis, dementia, Alzheimer’s disease, depression, and even glaucoma (2016).

Nootropic Benefits of Ginkgo Biloba

Memory, Concentration, Brain Booster

MEMORY-KEYS

Ginkgo Biloba has been used for thousands of years for its studied ability to improve memory, concentration, and overall brain function.  A lot of the plant’s contributions in this realm can be traced to its benefits to cerebral blood flow and circulation (Chevallier, 2016).  Improving cerebral circulation gives memory and concentration a giant boost (2016). Many studies have greatly outlined the plant’s ability to improve both short-term and long-term memory, and the cerebral circulation boost has a lot to do with the efficacy of such benefits (Balch, 2010).  Some studies indicate an improvement to the peripheral circulation system, also promoting brain function and memory (2010). These same studies have backed up claims that Ginkgo can enhance concentration (2016).   One holistic encyclopedia even suggests the herb can protect the brain (Murray & Pizzorno, 1998)

Antioxidant

Ginkgo is known for its potent antioxidant effects, especially within the brain, cardiovascular system, and retina (Balch, 2010).  The impressive flavonoid content within the plant boasts powerful longevity effects (Murray & Pizzorno, 1998).  Due to these outstanding benefits to the body, the plant has been considered throughout Chinese holistic healing history as an anti-aging herb. They also respected the plant for its ability to improve the body’s resistance to the environment (1998).  The antioxidant properties of Ginkgo Biloba are one of the reasons the herb is so popularly prescribed around the globe in the medicinal world (Beshara & Haynes, 2019). The potent antioxidant effects are also one of the reasons Ginkgo offers such positive effects in terms of improve cognitive function (Kaur et al., 2018).

Anti-Inflammatory

GINKO-FRUIT

Ginkgo possesses amazing anti-inflammatory properties, even being able to reduce inflammation where there is nerve tissue damage (Chevallier, 2016). This has especially proven helpful for multiple sclerosis patients.  And that makes sense, since the plant provides enhanced blood flow to the central nervous system.  It has even been suggested to strengthen and support nerve tissue (2016). Chinese medicine has long turned to Ginkgo for the anti-inflammatory effects its fruit and seed possess, often referring to it as a tonic for the body (Orr, 2014). Many recent studies are showing Ginkgo to have the ability to significantly decrease oxidative stress and reduce neuroinflammation (Kaur et al., 2018).

Circulatory Issues

Ginkgo is well known for its ability to enhance circulation with numerous published empirical studies, even in the Journal of the American Medical Association (Balch, 2010). The leaves of the Ginkgo plant produce some of the plant’s most potent medicinal properties for improving circulation and blood flow (Chevallier, 2016). The Ginkgo leaves are usually extracted to make a strong tincture, liquid extract, or pill/tablet. And as previously mentioned, these extracts have especially been useful in improving cerebral circulation.  The plant’s ability to inhibit the platelet activating factor (PAF), reduces the likelihood of a blood clot and stroke (2016).

Ginkgo Biloba is also a purported, natural treatment for erectile dysfunction.  One study revealed that participants were experiencing more erections (Murray & Pizzorno, 1998). In fact, the erections were not just more frequent, but also improved in quality and duration.  This is probably due to the herb’s ability to improve circulation and blood flow.  Other studies revealed the plant’s ability to offset sexual dysfunction caused as a side effect of antidepressant drugs (1998). It is also worth noting that the plant is great at improving blood flow to the lower region of the body (Conkling & Wong, 2006).

Dementia, Alzheimer’s Disease, and Many Neurological Conditions

Truly, the jury is still out on how effective Ginkgo Biloba may be as a treatment for Alzheimer’s and Dementia, however, there are many clinical studies which have found a variety of positive benefits (Chevallier, 2016).  Even this smaller collection of empirical data promoting the benefits of the natural herb for those suffering from neurological or brain-related conditions is encouraging.  As previously mentioned, the herb’s ability to improve memory (2016) is most certainly useful for those suffering from memory loss due to age or a neurodegenerative condition.  One recent study proved its substantial benefit to dementia patients (Balch, 2016).  And the plant is even shown to slow the progression of Alzheimer’s disease altogether (2016).

As previously mentioned, Ginkgo Biloba can provide significant benefits to patients suffering from multiple sclerosis (Murray & Pizzorno, 1998).  The herb has been empirically proven to improve cognitive impairment and overall mental function in MS patients.  It is able to improve attention, executive function, and memory performance (1998).  There are even studies which purport that the herb has a positive effect on anxiety (Beshara & Haynes, 2019).

Other Benefits

The seeds of the Ginkgo plant are commonly prescribed by Chinese medical professionals for issues with the urinary tract or the bladder (Chevallier, 2016). They are also brilliant for reducing wheezing and treating a general cough, although it is important to remember to remove the husk of the seed first, which only contains toxins and none of the plant’s useful constituents. The seeds also help reduce excess phlegm, treat vaginal discharge, and improve incontinence (as well as other bladder issues) (2016).  In Ayurvedic practice, the herb was traditionally used to manage cholesterol (Orr, 2014).

There is a lot of research which indicates Ginkgo Biloba can be used to treat depression and with great efficacy (Chevallier, 2016). It has especially good antidepression effects on individuals over the age of 50, or patients who suffer from cerebrovascular insufficiency (Murray & Pizzorno, 1998). Recent studies have outlined the plant’s great ability to aide recovering stroke patients (Balch, 2010).  It has also been used to treat hearing problems, macular degeneration, and impotence (2010).  It is reasonable to argue that the Ginkgo plant is one of the most diverse holistic herbs on the planet.

Dosing and Usage Information

Although there are many ways to prepare the Ginkgo plant, a tincture or tablet is one of the most common methods for consumption.  There are many high quality Ginkgo biloba extracts sold as dietary supplements, which usually suggest a dose of around 120 to 300 mg per daily pill.  This is also the dosage noted as safe in most holistic resources (Beshara & Haynes, 2019). 

It is worth noting that there are differences between preparation methods in terms of effects.  The traditional preparation method of a tincture extract (using the leaves only), is the best administration method when using Ginkgo for poor circulation, blood-related issues, or asthma (Chevallier, 2016).  Liquid decoctions of the seeds are the best way to use Ginkgo for wheezing, or treating a cough (2016).  The capsule/tablet method (usually consumed as a dietary supplement) is best for memory loss and most of the other benefits the Ginkgo plant offers (2016).

A standardized extract of Ginkgo Biloba is normally  24 percent flavoglycosides and 6 percent terpene lactones (Conkling & Wong, 2006).

Side Effects

Although the plant does have the potential to create some unpleasant side effects, they are minimal and rare.  Some of the side effects which have been reported in some studies include headaches, dizziness, upset stomach, constipation, tachycardia (fast heartbeat), and allergic skin reactions (Conkling & Wong, 2006).

Other Important Information

DOCTOR-PATIENT

It is important to note that Ginkgo Biloba can create issues for persons taking anticoagulants (blood-thinning medication) or those who regularly take over-the-counter pain medication (Conkling & Wong, 2006).  Although anyone who is considering adding a dietary supplement to their daily regimen should consult a physician beforehand, it is especially important for individuals on anticoagulants or OTC pain medicine to discuss Ginkgo with their doctors.  It should also not be used by anyone who is about to undergo surgery or a dental procedure.

Conclusion

The Ginkgo plant is an extremely versatile herb, possessing the ability to improve seemingly endless conditions and ailments. The studies, empirical data, clinical trials, and other research have shown the plant to offer incredible benefits with almost no side effects.  The side effects which do exist are minimal, trivial to say the least. In terms of treating neurological, neurodegenerative, or circulation issues, the plant is unbelievable and well-revered across the globe. Ginkgo is one of the most popular nootropic herbs for improving mental response times and memory, and maximizing learning potential (Orr, 2014).  To summarize, Ginkgo Biloba is a powerful and capable nootropic worthy of a place in nearly any nootropic stack.

A Note from NooFiles

This article is intended to be used for information only.  We want to remind you that consulting your physician is recommended before adding any dietary supplement of any kind to your daily regimen.

Sources:

Balch, P. (2010). Prescription for Nutritional Healing. Fifth Edition. Avery Publishing. New York, New York. ISBN 978-1-58333-400-3

Beshara, J., Engle, D., and Haynes, K. (2019). Beyond Coffee. Monocle Publishing. ISBN 9781544505459

Chevallier, A. (2016). Encyclopedia of Herbal Medicine. Third Edition. DK Publishing. New York, New York. ISBN 978-1-4654-4981-8

Conkling, W. and Wong, D. (2006). The Complete Guide to Vitamins and Supplements: The Holistic Path to Good Health. Avon Health Publishing. New York, NY. ISBN: 978-0-06-076066-3.

Kaur, S., Sharma, N., Nehru, B. (2018). Anti-inflammatory effects of Ginkgo biloba extract against trimethyltin-induced hippocampal neuronal injury. Inflammopharmacology. Vol. 26(1). Pp. 87-104. DOI: 10.1007/s10787-017-0396-2

Murray, M., and Pizzorno, J., (1998). The Encyclopedia of Natural Medicine. Third Edition. Atria Paperback. ISBN 978-1-4516-6300-6

Orr, S. (2014). The New American Herbal. Clarkson Potter Publishers. New York, New York. ISBN 978-0-449-81993-7

Roland, P. and Nergård, C. (2012). Ginkgo biloba–effekt, bivirkninger og interaksjoner [Ginkgo biloba–effect, adverse events and drug interaction]. Tidsskr Nor Laegeforen. Vol. 132(8). Pp. 956-9. Norwegian. DOI: 10.4045/tidsskr.11.0780