What Are The Best Supplements for Entrepreneurs?

Are There Supplements for Entrepreneurs?

Entrepreneurs are required to work harder. They work longer hours. In most cases, they have to be more efficient to succeed. It requires grit, persistence, investments, and tenacity. Fortunately, the entrepreneur can gain a bit of an edge by using the right daily supplements. Most of the supplements that are commonly found in an entrepreneur’s stack are considered “nootropics” (Denton, 2017). Most nootropics are natural herbs that provide a positive benefit to the mind or body, with very few negative side effects (Giurgea, 1983) (Gouliaev and Senning, 1994). There are, however, many synthetic drugs and supplements have also been accepted as nootropics (such as the racetams), so long as they enhance mental function or intellectual acuity.

Can Nootropics Be Used Together?

Nootropic supplements are very commonly used in various combinations to produce enhanced effects (Blokland and Sambeth, 2016). Some combinations may not be desirable due to cross-tolerance or adverse reactions from taking them at the same time, however, there are many stacks which are effective (Suliman, et al., 2016). There are also many pre-made proprietary formulae which are well-known to work (Angel, 2018). Depending upon the desired effects, it is possible to achieve a variety of benefits from combining some of the best nootropics in the same stack.

What is a Nootropics Stack?

Nootropic stacks, or proprietary formulae as they are called in the commercial industry, are groups of nootropics taken as a daily regimen. Some entrepreneurs create their own stacks, while others prefer to purchase premade proprietary blends which are formulated to produce very specific effects.

Nootropics that Boost the Entrepreneurial Edge

There are many supplements which benefit entrepreneurs. These are some of the most preferred (and most effective) nootropics chosen by top entrepreneurs (in alphabetical order).

*Highlighted nootropics are ingredients in one or more Pirate Botanicals products.

5-HTP (5-hydroxytryptophan) 

5-HTP crosses the blood-brain barrier freely and is directly converted into serotonin. It is not limited by biochemical feedback inhibition and is a natural source of amino acids (Hinz, et al., 2012). As a clinically-effective serotonin precursor, it is a well-absorbed, orally-dosed substance with about 70 percent carrying into the bloodstream (Birdsall, 1998). One study notoriously proved that 5-HTP is able to positively influence the brain to improve mood and ultimately efficiency (Shaw, et al., 2002). Another more recent study explained that 5-HTP can positively change “fundamental cognitive operations such as attention” (Weinburg, 2018).

Acetyl L-Carnitine

Acetyl L-Carnitine has been proven to provide neuroprotective benefits to cells, as well as offering antioxidant properties to the body (Wang, et al, 2020)(Karalija, et al., 2012). It is easily absorbed in the stomach, making it an excellent addition to many supplements and is known to reduce fatigue (Swanson, 2018).

Ashwagandha (Withania somnifera)

Ashwagandha has been traditionally used in a variety of cultures for thousands of years. It has a heavy history of use in Ayurvedic medicine. It is a rather popular supplement used by entrepreneurs for its stress-relieving properties. Although many studies involve subjects which are already experiencing stress, these are arguably the best participants for the research. These studies do typically reveal a profound anxiolytic effect on subjects, and suggest that the herb moderates the hypothalamus-pituitary-adrenal axis (Lopresti, et al., 2019). It is also known as Indian Ginseng.

Bacopa Monnieri

Bacopa monnieri is native to many parts of the world and also goes by the common name Indian Pennywort. Although Bacopa is a bit weaker in terms of cognitive influence, it has been proven to have a slight effect on memory (Pase, et al., 2012). Specifically, it helps slightly improve memory recall, though the other cognitive domains have been understudied (2012).

Citicoline

Citicoline is commonly among individuals whom have suffered cognitive impairment (dementia, stroke, Alzheimer’s, etc.) to improve memory loss. Entrepreneurs sometimes include citicoline in their nootropic stack for a small boost to mental energy and learning. Truthfully, however, the studies to support the benefits of citicoline in healthy brains are lacking.

Coluracetam

Coluracetam is a member of the racetam family, and it is frequently used to treat Alzheimer’s disease. Although it is typically only used from a reparative/therapeutic perspective in terms of cognition and memory aid, more recent studies are suggesting it may boost cognition for a health brain as well (Malykh and Sadaie, 2010).

GABA (Gamma-Aminobutyric acid)

GABA plays an important role as a neurotransmitter in the central nervous system and reduces neuronal excitability (Olsen, 2006). Sometimes it is used in stress relief and relaxation formulae. It works by binding with GABA receptors and invoking a calming effect in the brain (Westphalen, 2019).

Ginkgo Biloba

Also known as the Maidenhair tree, is only native to China. It is one of the oldest species of plants used as a nootropic, dating back hundreds of millions of years old (Sun, 1998)! It is a very commonly used nutraceuticals offering neuroprotective properties, stress relief, and mild memory enhancement (Mahadevan, 2008).

Ginseng, Siberian (Eleutherococcus senticosus) 

Ginseng is one of the most popular nootropics in entrepreneur supplements for its many offerings in terms of cognitive enhancement. Siberian Ginseng is often considered one of the best variants. It is an herbal adaptogen and antioxidant, helping the mind destress and feel clean (Abbai, 2016). It is believed to provide energy, combat fatigue, improve cognitive function, and improve stress response (Cohen, 2019).

Gotu Kola (Centella asiatica)

Gotu Kola is also known as Indian Pennywort. It grows in Asia and has been long revered for its medicinal and culinary uses. Gotu Kola is used in some entrepreneur stacks for its ability to improve blood flow and circulation (Gohil, et al., 2010).

Green Tea Extract 

Green Tea extract is a very common constituent in an entrepreneur’s nootropic stack for its many cognitive benefits. It is a powerful adaptogen that is much more effective than most other nootropics at reducing stress (Keiko, 2017). Still, Green Tea extract is able to provide stimulation as it literally contains natural caffeine. The natural caffeine is distributed to the mind and body more evenly than most other caffeine sources. This provides the mind a greater boost to concentration and focus (Godsey, et al., 2020).

Guarana (Paullinia cupana)

Guarana has been hailed among entrepreneurs one of the most effective ingredients in energy drinks and supplements. In recent years, it has been used as a caffeine substitute and antioxidant (Peixoto, 2017). Mostly, it is included in entrepreneur stacks for its light stimulating effects (although it is still no where near as strong as actual caffeine).

Hawthorn (Crataegus) 

Hawthorn is a bushy shrub that grows in temperate regions and yields bright red berries. It is well known in traditional Chinese medicine. Hawthorn is a powerful antioxidant and helps reduce stress levels (Strugala, et al., 2016). Both of these prime assets help entrepreneurs better function throughout their busy careers.

Huperzine A 

Huperzine A is an alkaloid compound that is extracted from the Chinese firmoss Huperzia serrata. It is also a big part of traditional Chinese medicine. It has a tremendous history fighting cognitive impairments, Alzheimer’s, and is considered an anti-dementia aid (Yue, et al., 2012). Huperzine A is one of the most popular nootropics in entrepreneur stacks for its favorable impact to cognitive function (Wessinger, 2018).

L-Theanine 

L-Theanine is an amino acid analogue and is a special constituent isolated from gyokuro leaves. It is capable of enhancing mental sharpness in the same way as meditation (Challem, 2007). It is frequently used to promote peace and calmness (2007). It is found in many entrepreneur stacks for its stress relieving properties and ability to promote focus.

Lemon Balm (Melissa officinalis)

Lemon Balm is sometimes used in entrepreneur nootropic stacks to reduce stress and induce sleep (Cronkleton, 2019). In fact, it has even been proven to be effective when it is contained in food (Scholey, et al., 2014).

Lion’s Mane Mushroom (Hericium erinaceus)

Lion’s Mane Mushroom goes by many names including “Monkey Head Mushroom,” “Bearded Tooth Mushroom,” and even the “Hedgehog Mushroom.” It is found growing on American Beech trees in the late summer to early fall. Frequently, it is found in nootropic stacks for its mild cognitive improvement and mood regulation benefits (Wiley, 2019).

Modafinil (Provigil and Nuvigil)

Many brand names for Modafinil exist, probably most famous of the bunch being “Provigil.” It is frequently hailed as a cognitive enhancer, but very little research suggests any efficacy in terms of cognitive improvement. It is still used to help treat sleepiness and is listed as a scheduled substance in the United States.

Noopept (N-Phenylacetyl-L-prolylglycine ethyl ester)

Although Noopept is not FDA approved, it is sometimes used by entrepreneurs for its purported neuroprotective and neuroregenerative properties. Truthfully, however, it has mostly only been studied in efficacy among people with traumatic brain injuries (Zainullina, 2019).

Passion Flower (Passiflora) 

Passion Flower (sometimes spelled Passionflower) are beautiful purple flowers which grow on vines that may come in the form of trees or shrubs. It has been used in traditional medicines for generations. Typically it is used for its sedative properties, for mild pain relief, and to reduce anxiety (NCCIH, 2016). It is a very common nootropic for entrepreneurs who need to relieve tension.

Phenibut

Phenibut is commonly used to reduce anxiety and improve sleep. Tolerance to phenibut builds rather quickly. And although it is an effective nootropics, side effects can be a little exhaustive, making it a less common choice for an entrepreneur stack (Lapin, 2001).

Piracetam

Although Piracetam is most commonly used to treat CNS disorders, it is found in a variety of nootropic stacks. Recent studies have revealed Piracetam is a somewhat promising candidate for being a neuroprotective and neuroregenerative nootropic (Malykh, 2010).

Rhodiola rosea 

Rhodiola is native to wild Artic climates and is a large part of many traditional medicines. It is known to reduce stress levels, decrease fatigue, and promote energy (Ishaque, 2010). It is a common constituent in energy and anti-fatique-based nootropic stacks (Zhang, 2009). It is frequently used by entrepreneurs to improve their overall alertness and focus.

Taurine

Taurine is commonly found in energy drinks. It is extracted from animal tissue, such as its original biosynthesis from ox bile (Tiedemann and Gmelin, 1827). It is also an antioxidant, helping the body to rid itself of cell-damaging free radicals (Xu, et al., 2008).

Tyrosine

Tyrosine is one of the body’s standard non-essential amino acids used to synthesize proteins. Although it is rather weak in terms of noticeable effects, it is a neurotransmitter precursor that stimulates the production of dopamine and norepinephrine (Rasmussen, 1983).

Valarian Root 

Valarian (Valeriana officinalis) is a sweet smelling plant that is native to Europe and Asia. Two primary alkaloids of interest, valerianine and valerine work by binding to the brain’s GABA receptors. Valarian is used in nootropic supplements for its calming, sedative, and peaceful effects (James, 2003).

Vinpocetine

Vinpocetine is a synthetic derivative, ultimately created from Vincamine extracted from Voacanga africana seeds. It is typically used to treat post-stroke victims, and people suffering from various forms of dementia (Liu, et al., 2019)(Zhang, 2018). While it has been proven that it does provide some cognitive benefits to those who already suffer cognitive impairments of some kind, there are very few studies which support these same cognitive benefits for healthy individuals.

Yerba Mate

Yerba Mate is native to South America and is traditionally brewed into a beverage. It is very commonly ingested to improve metabolic health and overall mood (Alkhatib and Atcheson, 2017). A more relaxed state of mind can help an entrepreneur maintain focus, work longer, and achieve more. Containing a small amount of caffeine, it is perhaps one of the best ways to ingest caffeine for its positive benefits, with none of the negatives side effects (Ghezelbash, 2020).

Yohimbe 

Yohimbe comes from the bark of one of two trees located in Africa or South America only. Yohimbe is very frequently used for its ability to increase blood flow. It is used to decrease impotence, improve athletic performance, enhance weight loss efforts, and so much more (NIH, 2016). Yohimbine, the primary constituent alkaloid in Yohimbe, is known to induce noradrenergic stimulation which enhances memory consolidation (Wingenfeld, et al., 2013).

A Few Words About Caffeine, Aniracetam, and Others

Caffeine is often considered to be a nootropic. The definition of nootropic literally states that there are no negative side effects to using nootropics, but many people experience adverse reactions from using caffeine (Temple, et al., 2017). While there are some positive benefits from using caffeine for most people, some people experience cardiovascular function impairments, sleep deprivation, and other problems (2017). Still, many sites will claim caffeine as a nootropic, erroneously. And despite the benefits many people receive from caffeine intake, it will never be a true nootropic.

Aniracetam was long thought to improve cognitive function and memory in human beings. It has also been credited for improving learning as well. The studies which have backed up the idea that aniracetam improves learning, are on subjects which have a cognitive impairment. Many recent studies have painted a different picture, investigating the effects of aniracetam on healthy minds instead. These studies have revealed the substance to have no positive effect on learning, memory, or cognitive function (Reynolds, 2018) (Phillips, 2019).

Using Nootropic Supplements Effectively

Entrepreneurs put in so many hours and so much work that it makes the most sense to maximize efficiency within reasonable means. The top combinations of nootropic stacks are one of the best ways to make the most use of time as an entrepreneur (Denton, 2017). Whether the stack is devised to create energy or enhance focus, or to improve fluid intelligence, having a daily regimen most certainly gives the entrepreneur a significant advantage (Suliman, et al., 2016). And with the wide variety of information available, it has become easier than ever for any entrepreneur to select the proprietary blend that works best for them!

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